Prayer for Pain Relief: A Good and Powerful Prayer to Help Reduce Discomfort

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Why Prayer for Pain Relief?

Pain relief can be difficult to come by, but that doesn’t mean you’re out of options when you suffer from physical discomfort or extreme pain. Whether it’s from an injury, illness, surgery, or the aftermath of an accident, you can find relief through the power of prayer. Here’s one prayer for pain relief that can be used to counter any type of physical suffering.

15 Effective Prayers for Pain Relief

Pain can be difficult to manage, and often it’s difficult to avoid. Whether you have an injury or illness that causes pain, or you’re just suffering from stress and anxiety, sometimes the pain can be too much to handle alone. That’s where prayer comes in handy! Prayer has many benefits, and one of them is to help relieve the discomfort and pain you may be experiencing. Read on if you want to learn how to pray for pain relief with these seven prayers that really work!

The Lord’s Prayer (Jesus)

Father, hallowed be thy name. Thy kingdom come. Give us this day our daily bread, and forgive us our trespasses as we forgive those who trespass against us. And lead us not into temptation, but deliver us from evil. For thine is the kingdom, and the power, and the glory forever. Amen. (Luke 11:2-4)

2 Corinthians 4:16-18

Beautiful One, I will not be discouraged by the pain I feel! No, even if outwardly I am perishing, inwardly I am being renewed each and every day. This temporary suffering is producing for me an everlasting weight of glory, far beyond any comparison. I look not to the things that I can see, but for things that cannot be seen for they are eternal. Lord, this pain is insignificant when I focus on You and Your glory, Amen.

Revelation 21:4

Hallelujah to Your precious Name! You will wipe every tear from my eyes, and there will be no more death or sorrow or crying or pain when I reunite with You in heaven. All these things are gone forever! Lord, I bless Your Name, in spite of the pain that I feel, because I know that You will relieve me from it, Amen.

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Romans 8:17-18

God of Heaven, since I am Your child, I am Your heir, an heir of Your glory. But if I am to share Your glory, I must also share Your suffering. I understand that pain and suffering is necessary in this time, but what I suffer now is nothing compared to the glory that You will reveal to me later, Amen.

2 Corinthians 12:9-10

Gracious Lord, Your word says that Your grace is sufficient for me: for Your strength is made perfect in weakness. Therefore, in my current pain, I will glorify Your Name because the power of Christ rests upon me! I will take pleasure in my infirmities, reproaches, necessities, persecutions, and distresses for Your sake: for when I am weak, then I am strong. I declare that the pain I feel shall be relieved in Jesus’ Name, Amen.


Job 6:10

God of Peace, I take comfort in knowing that despite the pain that I feel, I have not denied the words of the Holy One. I still stand upon Your word and Your truth. I thank You for keeping me and for sustaining me in my pain. I declare healing and pain relief in my life, for You are my Awesome Healer. I shall be free from the pain that I feel, Amen.

1 Peter 5:9-10

Dear Lord, I will stand firm in the faith, knowing that other Christians are experiencing the same kinds of suffering throughout the world. Although I feel isolated by pain, I am not. And after I have suffered a little while, the God of all grace (You). Who has called me to Your eternal glory in Christ, will Himself restore, confirm, strengthen, and establish me! Amen.

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Psalm 50:15

Righteous God, I call to You in times of trouble. Right now, I am in trouble, the pain that I feel is unbearable. The pain that I feel has kept me bound for too long. But I know that You will save me, You will relieve me of my pain. I thank You for hearing my voice and for answering my prayer! Thank You for easing my pain and for filling me with peace, Amen.

Psalm 147:3-5

Hallelujah to Your Precious Name! You heal the broken-hearted and bandages their wounds. Through Your grace I am healed from the pain that I feel and am no longer crippled by it. You also count the stars and name each one. Father, You are great and very powerful. There is no limit to what You know! There is no limit to Your power! Amen.

Psalm 6:2

Have mercy on me, Lord, for I am faint; heal me, Lord, for my bones are in agony. I am in excruciating pain, but I choose to turn to You because I know that only You can heal me. Only You can ease the pain that I feel. I thank You for Your mercy, I thank You for Your divine healing power, for without it, I would not have the pain relief that You freely give to me, Amen.

Psalm 68:19

Awesome Creator, You deserve praise! Day after day You carry my burden, You are my God who delivers me. I know that You will deliver me from the intense pain that I feel. I know this because You are a God who delivers; the Lord, the sovereign Lord, can rescue from death. You save me from distresses and heal me from my brokenness. Thank You for also relieving me of my pain, Amen.

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Psalm 18:2

Eternal Saviour, You are my rock and my fortress and my deliverer! My God, my rock in whom I take refuge, my shield and the horn of my salvation, my stronghold. The pain that I feel cannot outweigh the power that You have in my life. I seek You, my refuge, and reliever-of-pain. Thank You for being my strength and shield in times of great difficulty, Amen.

Hebrews 7:25

Father in Heaven, Your word tells me that Your son is able to save (heal and preserve) those who come to You, because You always live to intercede for them. I know that I shall be healed from my pain because Your son works on my behalf for my healing. I thank You for the continuous work that You do to ensure that I can be made whole through You, Amen.

James 5:14-15

Precious Lord, I am sick and in pain. I pray over my body right now and anoint myself with oil in the name of the Lord, I know that my prayer of faith will make me well, I shall be relieved of my pain; You will raise me up. I will be delivered from my agony because I have declared it through prayer. Keep me in Your divine arms, remove all pain from my body, Amen.

The Serenity Prayer (Frankl)

It is possible to change your perspective in a moment and find peace. Prayer is one way that we can do that, especially if it’s a prayer like The Serenity Prayer: God grant me the serenity to accept things I cannot change, courage to change things I can, and wisdom to know there’s a difference. You can pray this simple prayer just about anywhere, at any time—just take a moment of silence each day to recite it quietly.